Targeted therapy for gastric cancer possible Gastric cancer, otherwise known as stomach cancer, does not respond well to existing treatments and it is currently the third leading cause of cancer death in the world (after lung and liver cancer). Researchers have discovered that certain drugs, currently used to treat breast, ovarian and pancreatic cancers, could also be used to treat certain gastric cancers with a particular pattern of mutations
Autophagy works in cell nucleus to guard against start of cancer Autophagy, the degradation of unwanted cellular bits and pieces by the cell itself, has been shown for the first time to also work in the cell nucleus. In addition, in this setting autophagy plays a role in guarding against the start of cancer and is related to the aging process
Big data analysis platform to unveil gene interactions in cancer A breakthrough in cancer genomics has been achieved by developing a novel big data analysis platform for analyzing the interactions among genes. The analysis platform unveils the unregulated patterns of gene network in cancer and discovers potential diagnostic and therapeutic target genes, Nucleophosmin and its associated genes, in Chronic Myelogenous Leukemia
Erectile dysfunction drugs unlikely to cause melanoma A rigorous analysis of more than 20,000 medical records concludes that erectile dysfunction drugs are not a cause of melanoma, an often deadly form of skin cancer.. For the study, researchers matched and analyzed the medical records of men whose care was being monitored in Sweden, one of the few countries in the world taking a population-wide approach to battling melanoma.
Researchers develop new breath test to diagnose oesophageal, gastric cancer A breath test that can help doctors diagnose the early signs of esophageal and gastric cancer in minutes has been developed by researchers. Researchers analysed breath samples of 210 patients using the test.
Helicobacter pylori infection leaves a fingerprint in gastric cancer Several bacterial infections are now suspected to play a role in the development of cancer but for none is the link so conclusively proven as for H. pylori, which can induce chronic gastritis and ulcer disease, and ultimately lead to the development of cancer. After an infection with Helicobacter pylori, gene activity in the gastric cells resembles the activity of cancer cells.
Lymph nodes signal more aggressive thyroid cancer even in young patients Patients older than age 45 with thyroid cancer that has spread to neck lymph nodes have long been considered at higher risk of dying, but the same has not been true for younger patients. Younger thyroid cancer patients with lymph node involvement are also at increased risk of dying contrary to current beliefs and staging prognostic tools that classify young patients as having low-risk disease.
New tool on horizon for surgeons treating cancer patients Surgeons could know while their patients are still on the operating table if a tissue is cancerous, according to researchers who describe an automated droplet-based surface sampling probe that accomplishes in about 10 minutes what now routinely takes 20 to 30 minutes
Single gene turns colorectal cancer cells back into normal tissue in mice Anti-cancer strategies generally involve killing off tumor cells. However, cancer cells may instead be coaxed to turn back into normal tissue simply by activating a single gene. Researchers found that restoring normal levels of a human colorectal cancer gene in mice stopped tumor growth and re-established normal intestinal function within only four days.