Cancer cells poised for growth when opportunity knocks Researchers have identified a mechanism that allows cancer cells to respond and grow rapidly when levels of sugar in the blood rise. This may help to explain why people who develop conditions in which they have chronically high sugar levels in their blood, such as obesity, also have an increased risk of developing certain types of cancer.
Small RNA has big impact on prostate cancer microRNA, miR-124, reduced tumor growth and increased cell death in castration-resistant prostate cancer, new research concludes. This small RNA fragment hit multiple targets, reducing androgen receptor signaling and reviving the potency of enzalutamide, a treatment for advanced prostate cancer. In addition, miR-124 impeded EZH2 and Src, proteins that contribute to treatment resistance.
Metabolic profiles distinguish early stage ovarian cancer with unprecedented accuracy Studying blood serum compounds of different molecular weights has led scientists to a set of biomarkers that may enable development of a highly accurate screening test for early-stage ovarian cancer.
New tool uses 'drug spillover' to match cancer patients with treatments A new article describes a new tool that improves the ability to match drugs to disease: the Kinase Addiction Ranker predicts what genetics are truly driving the cancer in any population of cells and chooses the best 'kinase inhibitor' to silence these dangerous genetic causes of disease
Anti-inflammatory drug acts against ovarian cancer A non-steroidal anti-inflammatory drug (NSAID) called ketorolac helped women with ovarian cancer to survive longer, researchers report. Ketorolac, marketed as Toradol®, is approved for clinical use in the United States for pain after surgery.
Red grape chemical may help prevent bowel cancer but less is more Resveratrol, a chemical found in red grapes, is more effective in smaller doses at preventing bowel cancer in mice than high doses, according to new research. Previous research looked at high doses of purified resveratrol to study its potential to prevent cancer. This is the first study to look at the effects of a lower daily dose -- equivalent to the amount of resveratrol found in one large (approx. 250ml) glass of red wine -- comparing it with a dose 200 times higher.
New therapeutic strategy discovered for ovarian cancer Ovarian cancer is the deadliest of all cancers affecting the female reproductive system with very few effective treatments available. Prognosis is even worse among patients with certain subtypes of the disease. Now, researchers have identified a new therapeutic target in a particularly aggressive form of ovarian cancer, paving the way for what could be the first effective targeted therapy of its kind for the disease Continue Reading
New weapon in the fight against cancer could be in your body already A tool for keeping the most common forms of cancer at bay could be in your gut, a new study concludes. For the study, the research team tested thousands of chemicals found in the body with the help of a robot and discovered more than 20 that could delay the aging process, something inevitably linked to cancer Continue Reading
Breast cancer spread may be tied to cells that regulate blood flow Tumors require blood to emerge and spread. That is why scientists believe that targeting blood vessel cells known as pericytes may offer a potential new therapeutic approach when combined with vascular growth factors responsible for cell death Continue Reading
Popular Soda Ingredient Ups Cancer Risk Public health researchers have analyzed soda consumption data in order to characterize people's exposure to a potentially carcinogenic by product of some types of caramel color. Caramel color is a common ingredient in colas and other dark soft drinks. Continue Reading
Milk proteins show promise in prevention and treatment of cancer In a review of existing research, a team of Australian researchers found that milk proteins, consisting of short sequences called peptides, are potential candidates for the development of anticancer agents and can be generated by enzymatic action, such as those experienced during digestion or food processing, including fermentation. Their findings are in the recent issue of … Continue Reading
Potentially faster and more accurate mode of cancer treatment with new laser technology Surgeons rely on 200-year-old technology when removing cancer -- sight and touch -- to determine how much to remove and what to leave alone. Laser technology has the promise to help a surgeon better determine if an area is cancer or healthy tissue. Moreover, when combined with laser treatment for cancer, this work lays the groundwork for laser robotic treatment of cancer.Continue Reading
Promising drug target in certain breast and ovarian cancers Scientists indicate that the pool of patients who can benefit from the drug olaparib is potentially much wider – and offers a ready means of identifying them. Continue Reading
Novel strategy to prevent progression of inflammation-associated cancers By targeting the specific pathological function of the 'culprit' molecule rather than inhibiting its gene expression, new approach facilitates development of cancer drugs with fewer side effects Continue Reading
