Unusual drug target, drug generate exciting preclinical results in mouse models of metastatic breast cancer A doctor treating a patient with a potentially fatal metastatic breast tumor would be very pleased to find, after administering a round of treatment, that the primary tumor had undergone a change in character – from aggressive to static, and no longer shedding cells that can colonize distant organs of the body. Indeed, most patients with breast and other forms of cancer who succumb to the illness do so because of the cancer’s unstoppable spread.
Painkiller tapped to become future cancer-killer Diclofenac, a common painkiller, has significant anti-cancer properties, according to researchers. Like other drugs examined by the ReDO project, diclofenac is cheap and readily accessible -- and as it's already present in many medicine cabinets, it has been carefully tested.
Study reveals potential therapy targets for triple-negative breast cancer In cancer, cell signaling pathways are the critical chain of events that can either quash or quicken disease progression. A new study has revealed new information about how molecules called long non-coding RNAs (lncRNA) interact with HIF-1, a signaling pathway that is overexpressed in many cancers. HIF-1 has been shown to regulate breast cancer progression.
Irritable Bowel Syndrome caused by a foodborne pathogen Millions of people suffer from the effects of irritable bowel syndrome (IBS) — chronic bloating, abdominal pain, gas, diarrhea or constipation — although the malady itself, let alone the cause, has been notoriously difficult to diagnose. Now, however, a physician at Cedars-Sinai Medical Center in Los Angeles has developed two blood tests that can accurately detect the
GMO-Free label created by USDA The Agriculture Department has developed a new government certification and labeling for foods that are free of genetically modified ingredients. USDA’s move comes as some consumer groups push for mandatory labeling of the genetically modified organisms, or GMOs. The certification is the first of its kind, would be voluntary
CVS pays $22 million to resolve Florida Painkiller probe The U.S. Attorney’s Office in Tampa announced May 13 that CVS Health Corp., will pay $22 million in a settlement to resolve allegations that 2 of its pharmacies in central Florida sold painkillers that were not prescribed for legitimate medical purposes. Federal agents discovered that the pharmacies ordered about 3 million oxycodone pills in 2011 and ignored red flags that the prescriptions were not legitimate.
Study provides new insights into Clostridium spores Researchers have established how clostridia bacteria emerge from spores. This could help them understand how these bacteria germinate and go on to produce the deadly toxin responsible for botulism, a lethal form of food poisoning, or cause food spoilage.
Debate: Is the long term use of psychiatric drugs harmful? The benefits of psychiatric drugs have been exaggerated and the harms underplayed due to poor trial designs, argues an expert in a new article. But another expert and a patient contend that the evidence supports the use of these drugs.
Potential new painkiller provides longer lasting effects Medications have long been used to treat pain caused by injury or chronic conditions. Unfortunately, most are short-term fixes or cause side effects that limit their use. Researchers have discovered a new compound that offers longer lasting painkilling effects, and shows promise as an alternative to current anesthetics
New care approach to colorectal operations speeds patient's' recovery times Patients undergoing colorectal operations who participated in an enhanced recovery program left the hospital sooner and had significantly lower hospital costs than patients who had the traditional approach to their care, according to a new study, which also found further postoperative improvements after adding an infection prevention protocol
Snoring keeping you up at night? In patients with primary snoring or mild OSA, oropharyngeal, or mouth and tongue, exercises significantly reduced the frequency of snoring by 36 percent and total power of snoring by 59 percent, a study concludes