Cardiovascular research: How to improve cardiac arrest survival in three easy steps ♦ Seeking treatment earlier may improve heart attack outcomes ♦.Cardiovascular disease in adult survivors of childhood cancer

Seeking treatment earlier may improve heart attack outcomes While hospitals have made strides in reducing the time it takes to treat heart attack patients once they arrive at the hospital, patient delays recognizing symptoms and seeking treatment are associated with increased damage to the heart, according to a study.

Treatment time lags for heart attack patients with prior bypass graft surgery Heart attack patients who had previously undergone coronary artery bypass graft surgery were less likely than other heart attack patients, including those with prior angioplasty, to be treated within the 90-minute recommended 'door-to-balloon time,'

How to improve cardiac arrest survival in three easy steps Although survival rates for people who suffer cardiac arrest outside a hospital are extremely low in most places, emergency physicians propose three interventions to improve survival rates and functional outcomes in any community

.Cardiovascular disease in adult survivors of childhood cancer For adult survivors of childhood cancer, cardiovascular disease presents at an earlier age, is associated with substantial morbidity, and is often asymptomatic. According to researchers, the type and frequency of screening that should be used in this group is not clear.

:3-D pancreatic cancer may help predict clinical responses, ♦ New clues for blocking cancer gene ♦ Inherited gene increased risk of childhood cancer

Genetic testing could identify men at a 10-fold increased risk of testicular cancer A new study of more than 25,000 men has uncovered four new genetic variants associated with increased risk of testicular cancer. Testing for these variants combined with all 21 previously identified using genetic sequencing identified men with a 10-fold higher risk of testicular cancer.

Drug for digestive problem can extend survival for many advanced cancer patients Advanced cancer patients given a drug designed to relieve constipation caused by pain killers lived longer with less tumor progression than those who did not receive or respond to the drug, researchers report. This is the first study in humans to associate opioid blockade with longer survival. It suggests that methylnaltrexone, approved in 2008 for prevention of opioid-induced constipation.

Inherited gene variation linked to an increased risk of the most common childhood cancer For two generations of one family, inherited variation in the ETV6 gene linked to an increased risk of childhood acute lymphoblastic leukemia.

3-D pancreatic cancer organoid may help predict clinical responses, personalize treatments A new method to grow 3-D organoid cultures of pancreatic tumors directly from surgical tissue offers a promising opportunity for testing targeted therapies and personalizing treatments.

New finding offers clues for blocking cancer gene A new study suggests a potential new way to block Notch, one of the most common cancer-causing genes, without causing severe side effects. The Notch gene plays a role in many types of cancer. It's the most common cancer-causing gene in T-cell acute lymphoblastic leukemia. About 60 percent of children and adults with T-cell leukemia harbor a Notch mutation

Cancer Research: Scientists find evidence of how incurable cancer develops ♦ New test could help personalize treatment for common childhood cancer

Study reveals high rates of preventable cancers in Indigenous peoples of high-income countries New research highlights the scale and profile of cancer in indigenous peoples of the USA, Canada, Australia and New Zealand, revealing high rates of often preventable cancers including lung and cervical cancer, emphasizing the need for targeted prevention strategies in these populations

Decoding the microbial signature of aggressive form of breast cancer Researchers have identified, for the first time, an association between two microbial signatures and triple negative breast cancer, the most aggressive form of the disease.

New test could help personalize treatment for common childhood cancer A new gene test can identify which patients are likely to suffer more aggressive forms of the childhood cancer rhabdomyosarcoma, new research reports. Examining the activity of only five genes in a sample of the tumor was enough to identify high-risk children who might benefit from more intensive treatment or from new therapies in clinical trials.

Scientists find evidence of how incurable cancer develops Researchers have made a breakthrough in explaining how an incurable type of blood cancer develops from an often symptomless prior blood disorder. The findings could lead to more effective treatments and ways to identify those most at risk of developing the cancer.

Cancer Research: Cancer gene ends the life of cancer cells ♦ ‘best shot’ at fighting kidney cancer ♦ Most cancer patients want tumor profiling

Cancer gene unintentionally ends the life of cancer cells, turns off life supporting genes Myc cancer gene makes cells to commit suicide by repressing life supporting "well-being" genes. These findings provide new opportunities to develop drugs, which could switch Myc from a cancer driver gene to a deadly assassin of the cancer cells,

Clinical trial offers patient ‘best shot’ at fighting kidney cancer The pain Anne Holmes felt in her arm was actually kidney cancer that had spread. She joined a phase 3 clinical trial. The trial tests a new approach that strips the invisibility cloak from spreading kidney cancer cells; it will use Holmes' own cells to create a vaccine tailored for her cancer cells

Childhood cancer survivors more likely to claim social security support as adults Childhood cancer survivors are five times more likely to have enrolled in a Social Security disability assistance program than other citizens. "The long-term impact of cancer can affect other issues besides health outcomes, "We need to do a better job of helping people function throughout their lives, not just when they're finishing their cancer therapy."

Most cancer patients want tumor profiling, even if it reveals other genetic risks Most cancer patients would opt for tumor profiling even if the test revealed that they or their families were at risk for other genetic diseases. The study showed that despite the risk for receiving information about other potentially serious health problems, 59% of the cancer patients would agree to tumor profiling. In a scenario where tumor profiling was already ordered, 79% of patients stated they wanted to know all of the information obtained.