Health News: Diet To Lower Alzheimer’s Disease and Dementia Ranked Easiest ♦ Sheffield shop’s booze licence revoked after illegal alcohol seized ♦ New potential treatment for colorectal cancer discovered

Diet To Lower Alzheimer’s Disease and Dementia Ranked Easiest US News and World Report has just released its compiled survey on the Best Diets of 2016. Guess what? DASH diet continues to stay on top as the easiest to follow diet out of 38 popular healthy diets evaluated by health experts. The magazine surveyed a number of well-renowned experts who ranked the diets based on health benefits, nutritional

Sheffield shop’s booze licence revoked after illegal alcohol seized A Sheffield off-licence owner has been caught selling illegal booze in his shop – just six weeks after he was convicted for similar offences. Jigar Patel has had his licence revoked in relation to two off-licences he owned after Trading Standards inspectors found illegal alcohol. The illicit booze was discovered on sale just six weeks after Patel was convicted of similar offences …

New potential treatment for colorectal cancer discovered A small molecule drug combined with chemotherapy may deliver a synergistic benefit for colorectal cancer patients, new research suggests. has demonstrated the efficiency of a small molecule drug, PRIMA-1met, in inhibiting the growth of colorectal cancer cells. Colorectal cancer is the cancer of the large intestine

One hookah tobacco smoking session delivers 25 times the tar of a single cigarette As cigarette smoking rates fall, more people are smoking tobacco from hookahs: communal pipes that enable users to draw tobacco smoke through water. A new meta-analysis shows that hookah smokers are inhaling a large load of toxicants

Health Research: How you manage your emails may be bad for your health ♦ New paste prevents scarring caused by radiation therapy for cancer

New paste prevents scarring caused by radiation therapy for cancer An anti scarring paste when applied to the skin of mice halts fibrosis caused by the radiation used in cancer therapy, a new study demonstrates. The current study addressed a type of fibrosis called radiation dermatitis, which is a side effect experienced by as many as 95 percent of patients undergoing initial radiation treatment. Radiation applied to the skin causes the buildup of fibrotic tissue and skin thickening, with the effects severe enough in some patients to stop treatment.

How you manage your emails may be bad for your health It’s not just the volume of emails that causes stress; it’s our well-intentioned habits and our need to feel in control that backfires on us.

Virtual colonoscopy an alternative to FOB test, colonoscopy for colorectal cancer? Colorectal cancer is the third most diagnosed cancer in the world, with population screening being recommended for early disease detection, however, the most optimal method to screen for the disease remains unknown

Beyond dance: Ballet training improves muscle coordination in everyday activities Professional ballet dancers have more control over their muscles than individuals with no dance training.

Health Research:Fat cells originating from bone marrow found in humans ♦ Vision test gives insight into the effect of prenatal exposure to recreational drugs

City-wide effort boosts NYC's colorectal cancer screening rates Work to increase colorectal cancer screening rates in New York City have resulted in a 40 percent increase in screening rates over four years.

Treatment for sickle cell disease may help protect patients' kidney function After six months of treatment with hydroxyurea, sickle cell disease patients' kidney function, as measured by the urinary albumin/creatinine ratio, improved significantly.

Vision test gives insight into the effect of prenatal exposure to recreational drugs

Children exposed to marijuana in the womb show a significant improvement in their ability to track moving objects at age four. But researchers are warning that the results do not mean marijuana has a beneficial effect on fetal development.

Fat cells originating from bone marrow found in humans Fat cells produced by stem cells from the bone marrow may be linked to chronic illnesses like diabetes, cardiovascular disease, kidney disease and some cancers.

Cancer Research: Dead bacteria used to kill colorectal cancer ♦ Medicines for breast cancer: The affordability controversy ♦ How glucose regulation enables malignant tumor growth

Medicines for breast cancer: The affordability controversy New and better drugs to treat diseases such as advanced breast cancer will have little effect on improving patient outcomes if a country does not have good health-care structures in place.

How glucose regulation enables malignant tumor growth A new study identifies a key pathway used by cancer cells to make the lipids by integrating oncogenic signaling, fuel availability and lipid synthesis to support cell division and rapid tumor growth.

Flipping the switch to better see cancer cells at depths Using a high-tech imaging method, biomedical engineers were able to see early-developing cancer cells deeper in tissue than ever before with the help of a novel protein from a bacterium.

Dead bacteria used to kill colorectal cancer Scientists have successfully used dead bacteria to kill colorectal cancer cells.

Cancer Research: Lung cancer survival rates improve with CT scan follow-up ♦ COPD heightens deadly lung cancer risk in smokers ♦ Genetic screening of brain metastases reveals new treatment

Differences between tumors of younger and older colorectal cancer patients  Tumors in younger colorectal cancer patients may be molecularly distinct from those of older patients, and that these differences are related to the way genes are switched on and off (epigenetics) in the tumors of the younger patients and may lead to better treatment options.

Genetic screening of brain metastases could reveal new targets for treatment Unravelling the genetic sequences of cancer that has spread to the brain could offer unexpected targets for effective treatment

Lung cancer survival rates improve with CT scan follow-up Patients with recurrent lung cancer have better post-surgery survival rates if their management includes a follow-up program based on computer tomography of the chest.

Differences found between smokers and nonsmokers who develop lung cancer Tobacco smoke is known to be the main risk factor for non-small cell lung cancer (NSCLC), although non-smokers can get it too. The incidence among non-smokers is increasing in many countries. Now a group of researchers has found significant differences in clinical particularities and survival between smokers and nonsmokers who develop NSCLC.

COPD heightens deadly lung cancer risk in smokers Smokers who have chronic obstructive pulmonary disorder may face nearly twice the risk of getting small cell lung cancer -- the deadliest form of lung cancer -- than smokers who don't have COPD.

Cancer Research: Cancer patient receives 3-D printed ribs ♦ Cancer preventative surgery could become a thing of the past ♦ Improving a better class of cancer drugs

Key cellular enzyme could be effective drug target in urological cancer cells A key cellular enzyme, c-Abl, could be an effective drug target in cancer cells for urologic cancers, such as prostate and kidney, new research indicates. Ongoing research into treatments for kidney cancer is especially important since kidney cancer is known to be resistant to current chemotherapy

Cancer preventative surgery could become a thing of the past Two new studies looking at the effect the menstrual cycle has on the development of breast and ovarian cancer reveal alternative prevention strategies that may render surgery unnecessary

Cancer patient receives 3-D printed ribs After being diagnosed with a chest wall sarcoma, a 54-year-old Spanish man's surgical team made the decision to remove his sternum and a portion of his rib cage and replace it with an implant. This cancer patient has now received a 3-D printed titanium sternum and rib implant.

New epigenetic study reveals exciting insights into colorectal cancer progression New epigenetic markers for colorectal cancer have been identified by researchers, suggesting that there may be a new approach for treatment in sight

Improving a better class of cancer drugs A class of therapeutic drugs known as protein kinase inhibitors has become a powerful weapon in the fight against various life-threatening diseases. One problem with these drugs, however, is that they often inhibit many different targets, which can lead to side effects and complications in therapeutic use. A recent study has identified a new technique for improving the selectivity of these drugs and possibly decreasing unwanted side effects in the future.

Cancer Research: 'Nanopore' scanners to find early signs of cancer ♦ Long-term needs of colorectal cancer survivors ♦ Increased detection of low-risk tumors

Increased detection of low-risk tumors driving up thyroid cancer rates, study finds Low-risk cancers that do not have any symptoms and presumably will not cause problems in the future are responsible for the rapid increase in the number of new cases of thyroid cancer diagnosed over the past decade, according to a study. According to the study authors, nearly one-third of these recent cases were diagnosed when clinicians used high-tech imaging even when no symptoms of thyroid disease were present.

New drug-like compounds may improve odds of men battling prostate cancer Researchers have discovered new drug-like compounds that could ultimately be developed into medicines that offer better odds of survival to prostate cancer patients. The new compounds target the human protein P-gp, which causes resistance against a majority of the drugs currently available for treating cancer and HIV/AIDS. The new compounds, discovered via computer-generated models, are good candidates for development into drugs since the compounds have low toxicity to noncancerous cells

New guidelines address long-term needs of colorectal cancer survivors New American Cancer Society Cancer Survivorship Care guidelines released today provide primary care clinicians with recommendations for providing comprehensive care to the estimated 1.2 million survivors of colorectal cancer in the United States.

Researchers use 'nanopore' scanners to find early signs of cancer The tiniest of scanners could be a huge step forward in the fight against cancer. “Nanopore” scanners could save lives by detecting individual DNA molecules, making it possible to diagnose colorectal and lung cancers at their earliest stages.

Dental research effort aims to stem India's oral cancer problem New work has resulted in innovative techniques that utilize some of the world's most sophisticated lasers to noninvasively probe into mouth lesions to determine the growth of cancerous cells and eradicate them. Now, this focus is on stemming India's oral cancer problem with a portable diagnostic device.

Cancer Research: A new virus in liver cancer ♦ Tumour suppressor genes curb growth in neighboring cells ♦ Researchers thwart cancer cells by triggering 'virus alert'

A new virus in liver cancer More than a cause of a simple infection, viruses are often involved in the development of serious diseases. Such is the case with liver cancer, which often develops in an organ that has been weakened by hepatitis B or C virus. Researchers have just identified the role of a new virus, hitherto unsuspected, in the occurrence of a rare type of liver cancer.

New strategy improves detection of genetic mutations in hereditary colorectal cancer Enhanced accuracy and reduced turnaround time of testing can provide vital information for patients suspected of having lynch syndrome and their family members, according to a new report.

New synthetic tumor environments make cancer research more realistic Tumors are notoriously difficult to study in their natural habitat -- body tissues -- but a new synthetic tissue environment may give cancer researchers the next-best look at tumor growth and behavior. Researchers have now developed a new technique to create a cell habitat of hydrogels which can realistically and quickly recreate microenvironments found across biology.

Tumor suppressor genes curb growth in neighboring cells Researchers have unraveled a role for tumor suppressor genes in restricting the growth of neighboring cell populations. The study might have implications for understanding the early events of tumorigenesis and the selection of the tumour-initiating cells.

Researchers thwart cancer cells by triggering 'virus alert' Working with human cancer cell lines and mice, researchers have found a way to trigger a type of immune system 'virus alert' that may one day boost cancer patients' response to immunotherapy drugs. An increasingly promising focus of cancer research, the drugs are designed to disarm cancer cells' ability to avoid detection and destruction by the immune system.

Cancer Research:Nerve-guiding protein that aids pancreatic cancer spread ♦ Drug candidate kills cancer cells through over stimulation ♦ Advanced cell screening technology for cancer immunotherapy

Researchers identify nerve-guiding protein that aids pancreatic cancer spread Scientists have identified a molecular partnership in pancreatic cancer cells that might help to explain how the disease spreads -- metastasizes -- in some cases. Their findings reveal urgently needed new targets to treat pancreatic cancer, which strikes nearly 50,000 people in the US each year and has only a 5 percent survival rate five years after diagnosis.

Drug candidate kills cancer cells through overstimulation A drug candidate that overstimulates proteins crucial for tumor growth shows promise as a new strategy to treat a wide range of cancers. The demands of rapid cell division put a strain on cancer cells, and the approach works by tipping cell stress over the edge. Researchers show that the drug candidate inhibits tumor growth in a mouse model of breast cancer and efficiently kills a broad range of human cancer cells.

Poor survival among colorectal cancer patients tied to biomarker csn6 A protein called CSN6 has been found to be correlated with poor survival among patients with colorectal cancer, according to a study. The study revealed that CSN6, a subunit of a protein complex known as COP9 signalsome, is overexpressed in colorectal cancer tissue samples. The finding could be significant in the search for alternative treatment strategies for colorectal cancer.

Researchers develop advanced cell screening technology for cancer immunotherapy Researchers have created a new method for screening cells used in immunotherapy cancer treatments, allowing high-performing immune system cells to be studied in isolation and potentially expanding the number of patients for whom the breakthrough treatment proves successful.

Health Research: How St. John's Wort can make you sick ♦ Vaccines and treatment for dengue virus possible ♦ Sleep deprivation could reduce intrusive memories

Sleep deprivation could reduce intrusive memories of traumatic scenes A good night's sleep has long been recommended to those who have experienced a traumatic event. But a new study provides preliminary experimental work suggesting it could actually be the wrong thing to do.

Warts and all: How St. John's Wort can make you sick St John's Wort can produce the same adverse reactions as antidepressants, and serious side effects can occur when the two are taken together, according to new research.

Thin colorectal cancer patients have shorter survival than obese patients Although being overweight with a high body-mass index has long been associated with a higher risk for colorectal cancer, thinner patients might not fare as well after treatment for advanced cancer, according to a new study

People with epilepsy can benefit from smartphone apps to manage their condition While many people with epilepsy can control their seizures with medication, those unpredictable and involuntary changes in behavior and consciousness can be limiting for others. Neurologists evaluated the application of smartphones in epilepsy care. Apps include seizure diaries as well as medication trackers with reminders to take the next dose of medication. In addition, apps are available to answer any questions patients with epilepsy might have, to detect potential drug interactions and to detect seizures.

Vaccines and treatment for dengue virus possible Researchers have determined the structure of a human monoclonal antibody which, in an animal model, strongly neutralizes a type of the potentially lethal dengue virus.

Cancer Research: Compound in magnolia may combat cancer ♦ Earlier, easier detection of colorectal cancer ♦ Cancer drug makes fruit flies live longer

Compound in magnolia may combat head and neck cancers As one of the compounds in magnolia extract, honokiol has been used for centuries in traditional Chinese and Japanese medicine to treat anxiety and other conditions. More recently, scientists have been revealing its cancer-fighting properties.

New approach holds promise for earlier, easier detection of colorectal cancer A new, sensitive electrochemical technique capable of detecting colorectal cancer in tissue samples has been developed by chemists -- a method that could one day be used in clinical settings for the early diagnosis of colorectal cancer.

Cancer drug makes fruit flies live longer Adult fruit flies given a cancer drug live 12 percent longer than average, according to a study researching healthy aging. The drug targets a specific cellular process that occurs in animals, including humans, delaying the onset of age-related deaths by slowing the aging process.

New drug squashes cancer's last-ditch efforts to survive As a tumor grows, its cancerous cells ramp up an energy-harvesting process to support its hasty development. This process, called autophagy, is normally used by a cell to recycle damaged organelles and proteins, but is also co-opted by cancer cells to meet their increased energy and metabolic demands. A compound that stops this cellular recycling process has now been developed by scientists.

New class of compounds shrinks pancreatic cancer tumors, prevents regrowth A chemical compound that has reduced the growth of pancreatic cancer tumors by 80 percent in treated mice has been developed by researchers. The compound, called MM41, was designed to block faulty genes. It appears to do this by targeting little knots in their DNA, called quadruplexes, which are very different from normal DNA and which are especially found in faulty genes.

Cancer Research:Abdominal blood clots may indicate undiagnosed cancer ♦ Discovery may lead to targeted melanoma therapies ♦ Tests to gauge genetic risks for prostate cancer now are feasible

Abdominal blood clots may indicate undiagnosed cancer  A blood clot in an abdominal vein may be an indicator of undiagnosed cancer. The study also suggests that these clots predict poorer survival in patients with liver and pancreatic cancer.

Discovery may lead to targeted melanoma therapies Melanoma patients with high levels of a protein that controls the expression of pro-growth genes are less likely to survive. The research team found that the protein, called H2A.Z.2, promotes the abnormal growth seen in melanoma cells as they develop into difficult-to-treat tumors. H2A.Z.2 is part of the chromosome structure that packages genes, and has the ability to switch them on off.

New biomarkers might help personalize metastatic colorectal cancer treatment Metastatic colorectal cancer patients tend to live longer when they respond to the first line of chemotherapy their doctors recommend. To better predict how patients will respond to chemotherapy drugs before they begin treatment, researchers conducted a proof-of-principle study with a small group of metastatic colorectal cancer patients. The results revealed two genes that could help physicians make more informed treatment decisions for patients with this disease

Tests to gauge genetic risks for prostate cancer now are feasible Men with an elevated, genetically inherited risk for prostate cancer could be routinely identified with a simple blood or urine test potentially paving the way to better or earlier diagnosis. The study included 7,783 men with prostate cancer and 38,595 without the disease.

Discovery promises new treatments to thwart colon cancer Scientists have discovered how an immune system protein, called AIM2 (Absent in Melanoma 2), plays a role in determining the aggressiveness of colon cancer. They found that AIM2 deficiency causes uncontrolled proliferation of intestinal cells. Surprisingly, they also discovered that AIM2 influences the microbiota -- the population of gut bacteria -- apparently fostering the proliferation of 'good' bacteria that can protect against colon cancer

Food Research: Avocados may hold the answer to beating leukemia ♦ Chocolate for your heart ♦ Adult craze for human breast milk

Chocolate for your heart Eating up to 100g of chocolate every day is linked to lowered heart disease and stroke risk. The calculations showed that compared with those who ate no chocolate higher intake was linked to an 11% lower risk of cardiovascular disease and a 25% lower risk of associated death

Avocados may hold the answer to beating leukemia Rich, creamy, nutritious and now cancer fighting. New research reveals that molecules derived from avocados could be effective in treating a form of cancer. AML is a devastating disease and proves fatal within five years for 90 per cent of seniors over age 65. This new avocado-derived drug could one day significantly increase life expectancy and quality of life for AML patients

Researchers discover component of cinnamon prevents colorectal cancer in mice Adding cinnamaldehyde, the compound that gives cinnamon its distinctive flavor and smell, to the diet of mice, scientists have discovered that mice were protected against colorectal cancer

Adult craze for human breast milk purchased online poses serious health risks The recent craze for human breast milk amongst certain fitness communities, fetishists and chronic disease sufferers is ill advised say the authors of a new study. Failure of women to sanitize properly when expressing milk, the failure to sterilize equipment properly, and the improper or prolonged storage and transportation of milk can expose consumers to bacterial food-borne illnesses like any other raw milk.

Avoidant/restrictive food intake disorder: More than just picky eating A new commentary by experts reflects on the clinical impact of the diagnosis of Avoidant/Restrictive Food Intake Disorder, and the work that remains in terms of treatments and improved outcomes.

Cancer Research: Pinpointing natural cancer drug's true origins ♦ Controlling typhoid bacterium key to prevent gallbladder cancer♦ Colorectal cancer genetically different in younger patients

Pinpointing natural cancer drug's true origins For decades, scientists have known that ET-743, a compound extracted from a marine invertebrate called a mangrove tunicate, can kill cancer cells. By analyzing the genome of the tunicate along with the microbes that live inside it using advanced sequencing techniques, researchers have been able to isolate the genetic blueprint of the ET-743's producer--which turns out to be a type of bacteria

State regulations for indoor tanning could lead to a national regulatory framework A national regulatory framework designed to prevent and limit indoor tanning is needed to alleviate the cancer burden and reduce the billions in financial costs from preventable skin cancer.

Controlling typhoid bacterium key to prevent gallbladder cancer in India and Pakistan Controlling typhoid fever could dramatically reduce the risk of gallbladder cancer in India and Pakistan. The findings establish the causal link between the bacterial infection and gallbladder cancer, explaining why this type of cancer is rare in the West but common in India and Pakistan, where typhoid fever is endemic.

Phase 2 trial identifies genetic dysfunction that makes many types of cancer vulnerable to an immunotherapy Researchers have identified a genetic malfunction that predicts the effectiveness of response to a groundbreaking immunotherapy. The results of their Phase 2 clinical trial reveal that, regardless of its tissue of origin, tumors whose cells are deficient in repairing mismatched DNA sequences--and so preventing mutations--are far more susceptible to pembrolizumab than those that retain this ability.

Colorectal cancer genetically different in older and younger patients While the overall rate of colorectal cancer (CRC) is declining, CRC specifically among young patients is increasing. Previous studies have shown that CRC in patients younger than 50 years old tends to be more aggressive than CRC in older patients. A new study offers early evidence of genetic differences between CRC in young and old patients, possibly pointing toward different treatments and strategies in combating the young form of the disease.

Cancer Research: Revealing kidney cancer's secret ♦ Stress relief techniques help cancer patients ♦ Drug extends life of patients with metastatic colorectal cancer

New release of Glioblastoma Atlas sheds light on deadly disease  Robust new data added to the Ivy Glioblastoma Atlas Project changes the scope and impact of this publicly available resource for researchers and clinicians searching for treatments for this most deadly and aggressive of brain cancers, glioblastoma multiforme.

Revealing kidney cancer's secret An international team of scientists showed how renal cell carcinoma (RCC) reprograms its metabolism and evades the immune system. In addition, the study found that cancer grade has a major impact on this reprogramming. These results point to new therapeutic options for this particularly deadly cancer.

Stress relief techniques help cancer patients overcome fear of treatment The benefit of rapid stress management techniques to help cancer patients who experienced 'procedure-related' stress has been revealed by a new study. Patients experiencing distress related to medical procedures were able to achieve a 'calm state' both before and during procedures as a result of the interventions.

Drug extends survival of patients with metastatic colorectal cancer  A drug developed 50 years ago and abandoned because it was considered to be too toxic has gained a second life in an international clinical trial. Research shows the drug and a potentiating agent lengthened the lives of patients with metastatic colorectal cancer, all of whom had exhausted available standard treatments.

Experimental immunotherapy shows high response rate in advanced lung cancer An early phase study testing an anti-PDL1 agent in combination with standard chemotherapy in the treatment of advanced non-small cell lung cancer has provided promising early results, prompting multiple phase III studies in lung cancer.

Many people are not getting the recommended cancer screening tests

• Cancer screening tests save lives, but test use falls short of nation’s goals
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• Are you current on all your recommended cancer screenings?
• This Mother’s Day, make sure you can celebrate with your family for years to come.
• Cancer screening saves lives.
• Cancer Screening Tests
• Many adults in the U.S. are not getting the recommended screening tests for colorectal, breast and cervical cancers, according to data published in the Centers for Disease Control and Prevention’s (CDC) Morbidity and Mortality Weekly Report. For 2013, screening for these types of cancers either fell behind previous rates or showed no improvement.
• Among adults in the age groups recommended for screening, about 1 in 5 women reported not being up-to-date with cervical cancer screening, about 1 in 4 women reported not being up-to-date with breast cancer screening, and about 2 in 5 adults reported not being up-to-date with colorectal cancer screening.
• The report found that colorectal cancer testing was essentially unchanged in 2013 compared with 2010. Pap test use in women age 21-65 years was lower than 2000, and the number of mammography screenings was stagnant, showing very little change from previous years.
• “It is concerning to see a stall in colorectal cancer screening rates,” said Lisa C. Richardson, M.D., M.P.H., director of CDC’s Division of Cancer Prevention and Control. “We must find new ways to make people and providers aware that getting tested for colorectal cancer could prevent cancer and save their lives.”
• Researchers reviewed data from the National Health Interview Survey 2013, which is used to monitor progress toward Healthy People 2020 goals for cancer screening based on the most recent U.S. Preventive Services Task Force guidelines.
• The screening data for 2013 show that 58.2 percent of adults age 50-75 years reported being screened for colorectal cancer; 72.6 percent of women age 50-74 had a mammogram; and 80.7 percent of women age 21-65 had a Pap test. All of these percentages are below the Healthy People 2020 targets.
• The report found that adults without insurance or a usual source of healthcare generally had the lowest screening test use. For example, fewer than one quarter of adults in these groups reported recent colorectal cancer screening, compared with more than 60 percent of adults with private insurance or a usual source of healthcare. More efforts are needed to achieve cancer screening goals and reduce screening disparities.
• The authors did report some good news: the proportion of women in the highest education and income groups who were screened for breast cancer exceeded the Healthy People 2020 target, and the proportion of people age 65-75 who were screened for colorectal cancer was also near the target.
• Through the Affordable Care Act, more Americans will qualify to get health care coverage that fits their needs and budget, including important preventive services such as screening for some cancers that may be covered with no additional costs. Visit Healthcare.gov or call 1-800-318-2596 (TTY/TDD 1-855-889-4325) to learn more.
• CDC’s Efforts to Increase Cancer Screening
• The Colorectal Cancer Control Program provides funding to 25 states and 4 tribes across the U.S. The program supports population-based screening efforts and provides colorectal cancer screening services to low-income men and women age 50–64 years who are underinsured or uninsured for screening, when no other insurance is available
• The Screen for Life: National Colorectal Cancer Action Campaign informs men and women aged 50 years and older about the importance of having regular colorectal cancer screening tests.

Cancer Research: Aspirin fights colorectal cancer and cervical cancer ♦ Researchers solve a lingering mystery of cancer cell biology ♦ Bowel cancer patient exercise to achieve health benefits

Two-thirds of bowel cancer patients aren't advised to exercise despite health benefits More than two-thirds of bowel cancer patients say they weren't advised to exercise regularly after their diagnosis – despite evidence that brisk physical activity is linked to better survival in bowel cancer.

Frequent aspirin use reduces risk of cervical cancer by nearly half Long-term and frequent use of aspirin is associated with significantly decreased risk of cervical cancer, according to a study.12,900 new cases of cervical cancer will be diagnosed and 4,100 women will die from the disease in 2015.

Settling an old debate: Researchers solve a lingering mystery of cancer cell biology German biologist Theodor Boveri observed early in the last century that cancer cells often harbor multiple copies of a subcellular structure that he had previously named the centrosome. He was also the first to suggest that the extra centrosomes drive cancer. Biologists have since learned a great deal about the structure and many functions of Boveri’s “special organ of cell division.” But why cancer cells harbor multiple copies of this organelle has remained unanswered. So has the question of whether healthy human cells even require centrosomes to divide. Now, 101 years after Boveri aired his suspicions, a paper may have some answers.

How aspirin fights colorectal cancer Taking aspirin reduces a person's risk of colorectal cancer, but the molecular mechanisms involved have remained unknown until a recent discovery. found that aspirin might exert its chemopreventive activity against colorectal cancer, at least partially, by normalizing the expression of epidermal growth factor receptor (EGFR) in gastrointestinal precancerous lesions. EGFR is overexpressed in about 80 percent of cases involving colorectal cancer, the third-leading cause of cancer-related death in the United States.

Cancer Research: Proposed breast cancer screening would increase deaths ♦ Toxic mushroom-based drug for colorectal cancer ♦ Personalized pancreas cancer clinical trial

Proposed breast cancer screening guidelines would increase deaths, experts say The breast cancer screening guidelines proposed yesterday by the United States Preventive Services Task Force would result in thousands of additional and unnecessary breast cancer deaths each year, according to radiologists at Loyola University Health System

Higher-than-expected pediatric cancer rates identified in two Florida areas Higher than expected rates of pediatric cancers have been identified in the Miami metro area and an area west of the Everglades. Comparisons across analyses reveal characteristics of the detected patterns, including the number of cases , types of cancer, racial composition and timing of the cluster west of the Everglades

How to conduct a personalized pancreas cancer clinical trial Leaders of an ongoing pancreatic cancer clinical trial known as the Individualized Molecular Pancreatic Cancer Therapy or 'IMPaCT' trial, have been learning ways to bring about about a new paradigm of personalized cancer care for pancreatic cancer and other aggressive cancer types.

Immune therapy tested in study of women with triple-negative breast cancer Early data in a preliminary human study show that an experimental immune system drug is generally safe and well tolerated in women with metastatic, triple-negative breast cancer, a persistently difficult form of the disease to treat.

Toxic mushroom-based drug may help battle colorectal cancer For some time, cancer scientists have considered the toxin, alpha-amanitin derived from “death cap” mushrooms, as a possible cancer treatment. However, due to its penchant for causing liver toxicity, its potential as an effective therapy has been limited.