Carbapenem-resistant Klebsiella pneumoniae known as CRKP is resistant to all antibiotics but one, colistin. Unfortunately colistin can damage the kidneys. Because CRKP has two membranes it is difficult to kill even with colistin.
. Klebsiella has been a harmless bacteria that lives in our intestine. Because of the overuse of antibiotics it has developed into CRKP that is antibiotic resistant. Bacteria can pass their DNA to other bacteria that they are touching. CRKP has already past its resistance to one species of E Coli This is one of the reason that drug resistance is spreading so quickly. So far there is only one totally drug resistant bacteria but more are expected in the near future.
The main way CRKP is spread is by people touching each other. In one hospital that was having a CRKP epidemic they found out that the health care workers only washed their hands between patients 48% of the time. There is a new product on the market that requires health care workers to wear a badge that has GPS tracking If a healthcare worker goes to a patient without stopping by the sink the badge busses to remind the health care worker to wash their hands. It is time all hospitals get this system. CRKP can also be spread to the lungs via a ventilator, through an IV catheter or through urinary tract catheter. It can also be spread by sharing clothing, razors or sporting equipment. . .
CRKP can cause a variety of illnesses, most commonly pneumonia, It also causes inflammation of the membrane that covers the brain and spinal cord, urinary tract infections, wound infections and blood infections, It can also cause infected surgical site infections.
To continue to ignore the fact that phage therapy can treat any bacterial disease is a travesty We need to encourage the FDA to change their attitude about phage therapy. . .
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