In a Centers for Disease Control and Prevention study identified increasing resistance to a class of drugs called Cephalosporins, which are commonly used to treat severe Salmonella infections in adults and children.
Currently, about five percent of Salmonella strains are resistant to Cephalosporins. These Salmonella strains produce beta-lactamase enzymes that breaks down cephalosporins and thereby confers resistance to the bacteria that produces this enzyme. Of concern to the researchers is the fact that the genes related to antimicrobial resistance are often mobile, moving between bacteria and Salmonella subspecies.
There is a new form of RNA called ExRNA which goes outside bacteria and spreads genetic material from one bacteria to another. This is one way drug resistance can be spread.
Drug resistance within the subspecies, Salmonella Kentucky, has largely increased overseas in recent years, posing a significant problem in Africa and the Middle East and sounding an alarm among researchers in the U.S.
“If it comes to this country and gets into our poultry farms, we will run out of antibiotics to treat it,” said Susan Vaughn Grooters, food-safety research and policy associate at the Center for Science in the Public Interest.
Resistance that was first observed in Indonesia, than in India, Pakistan and the Middle East. Then it then spread to Europe and very recently has emerged in Canada and the U.S. Consumer awareness of resistance and a demand for transparency surrounding it is important, as is increased regulation regarding antibiotic use.
Still Doctors prescribe antibiotics regularly for nasal infections which have been shown to be mostly viral.
It is urgent that we use Phage Therapy to fight bacterial diseases. It is not affected by drug resistant and does not have the side effects of antibiotics..
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