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Monday, June 29, 2015

Cancer Research: Potential new class of cancer drugs developed ♦ Experimental treatment sends deadly leukemia into remission ♦ microRNA may provide therapy against pancreatic cancer

microRNA may provide therapy against pancreatic cancer Cancer researchers have found that a particular microRNA may be a potent therapeutic agent against pancreatic cancer. The need for new therapies for pancreatic cancer patients is great as only 7 percent of people with the disease survive more than 5 years after diagnosis. According to the National Cancer Institute, there will be an estimated 48,960 new cases of pancreatic cancer and 40,560 deaths from the disease in 2015.
E2F4 signature can predict progression of bladder cancer Investigators harnessed genomic data to discover that the previously identified E2F4 signature in breast cancer can be utilized to predict prognosis and response to therapy in bladder cancer.
Experimental treatment sends deadly leukemia into remission An experimental new treatment approach for a rare, deadly leukemia can send the disease into remission even in patients for whom the standard therapy has failed, a pilot study has found. The study is 'proof of principle' the cutting-edge approach could be used to treat many other cancers as well.
Development of new blood vessels not essential to growth of lymph node metastases The growth of metastases in lymph nodes -- the most common site of cancer spread -- does not require the development of new blood vessels, researchers have discovered, potentially explaining why antiangiogenesis drugs have failed to prevent the development of new metastases.
Potential new class of cancer drugs developed A new class of drug developed targets the Warburg effect to cut off cancer's energy supply, and researchers say that it has the potential to stop most kinds of cancer in its tracks.

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