Cancer Research: Antibody-drug compounds and immunotherapy to treat breast cancer ♦ Drug may prevent life-threatening muscle loss in advanced cancers

Investigational drug may prevent life-threatening muscle loss in advanced cancers New data describes how an experimental drug can stop life-threatening muscle wasting (cachexia) associated with advanced cancers and restore muscle health. The experimental agent, known as AR-42 while in testing, was tested in preclinical studies

Detecting cancer cells before they form metastases A new method to detect cancer cells in the blood before they settle in the tissue and form a new tumor has been developed by a team of researchers. To date, it has been difficult to detect cancer cells in the blood at an early stage: about one malignant cell is encountered per billion of healthy cells.

Anticancer agent FL118 more potent than its analogs, not prone to typical channels of resistance A new synthetic form of camptothecin appears to have greater potency, longer efficacy and fewer adverse side effects than irinotecan and topotecan.

Antibody-drug compounds and immunotherapy to treat breast cancer To more efficiently treat breast cancer, scientists have been researching molecules that selectively bind to cancer cells and deliver a substance that can kill the tumor cells, for several years. Researchers have now, for the first time, successfully combined such an antibody-drug conjugate with a therapy that stimulates the immune system to attack tumor cells. This opens the door to new therapeutic options in the treatment of breast cancer