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Friday, December 18, 2015

Cancer Research: Probing the mystery of how cancer cells die ♦ Scientists uncover process that could drive the majority of cancers ♦ Novel strategy to target cancer-causing protein

Research reveals promising novel strategy to target cancer-causing protein The mechanism by which tumor cells elevated levels of MDM4, a protein that is highly expressed in cancer cells but not in normal adult tissues, has been revealed by researchers. The team has also found that the mechanism can be interfered with antisense oligonucleotides to suppress cancer growth.

Cancer: Pinpoint targeting instead of shotgun approach, say experts Integrins help cells communicate with and adapt to their environment. Also cancer cells depend on their properties to survive and spread throughout the body. Now scientists have successfully developed a small, highly active molecule that binds to a specific integrin that operates in many types of cancer. In the future it may allow patient-specific diagnoses and subsequent targeted treatment of tumor cells

Probing the mystery of how cancer cells die The role sphingolipids play in the death of cancer cells is now better understood, thanks to a recent study. The research traces how levels of various sphingolipids spike inside cancer cells when the cells are undergoing a highly organized form of cellular death called apoptosis.

Scientists uncover process that could drive the majority of cancers in The gene p53 has been described as the 'guardian of the genome' due to its prominent role preventing genetic mutations. More than half of all cancers are thought to originate from p53 mutations or loss of function, and now a recent study explains why.

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