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Wednesday, December 23, 2015

Heart structural gene causes sudden cardiac death in animal model ♦ Drugging the microbiome may treat heart disease ♦ Hypertension-related visits to emergency rooms on rise in US

Heart structural gene causes sudden cardiac death in animal model The presence or absence of the CAP2 gene causes sudden cardiac death in mice. In particular, the absence of the gene interrupts the animal's ability to send electrical signals to the heart to tell it to contract, a condition called cardiac conduction disease. Since humans have the same CAP2 gene, what we learn from the mice could advance our understanding of heart disease.
Drugging the microbiome may treat heart disease A first-of-a-kind drug that interferes with the metabolic activity of gut microbes could one day treat heart disease in humans, according to a mouse study. Dietary supplementation with a compound that is naturally abundant in red wine and olive oil prevented gut microbes from turning unhealthy foods into metabolic byproducts that clog arteries
Hypertension-related visits to emergency rooms on rise in US The number and percentage of patients treated at emergency departments for hypertension are on the rise across the United States.
Chances of good outcome after stroke reduced by delays in restoring blood flow Delays in restoring blood flow after a stroke were associated with decreased benefits of intra-arterial clot-busting treatment and reduced chances for a good outcome.

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