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Tuesday, November 10, 2015

Health Research: Early warning found for chronic kidney disease ♦ Gut microbiota regulates antioxidant metabolism ♦ Racial disparities associated with living kidney donation

Gut microbiota regulates antioxidant metabolism Gut microbiota regulates the glutathione and amino acid metabolism of the host. Glutathione is a key antioxidant, found in every cell in our body. Deficiency of glutathione contributes to oxidative stress, which plays a major role in several lifestyle diseases.
Early warning found for chronic kidney disease A simple blood test for the suPAR protein can predict a person's chances of developing chronic kidney disease five years before symptoms emerge, thus doing for kidney disease what cholesterol has done for cardiovascular disease.
Racial disparities associated with living kidney donation assessed Increasing median income levels of transplant candidates' zip codes were associated with higher rates of living donation, but African American candidates living in the wealthiest neighborhoods had only slightly higher rates than rates seen among the lowest median income areas for Caucasians.African-American donors had higher rates of complications early after donation
Gut microbiota changes in diabetic kidney disease contribute to chronic inflammation and vascular complications Among patients with type 2 diabetes and advanced chronic kidney disease (CKD), a shift in gut microbiota diversity in combination with elevated plasma zonulin levels substantially impacts the degree of chronic inflammation and endothelial dysfunction. Zonulin could be a potential future target to control inflammatory immune responses.

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