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Friday, December 4, 2015

Heart Research: Genetic link between heart and neurodevelopmental disease ♦ Genes linked to stress-triggered heart disease identified ♦ arterial thrombus formation

First outcomes report from novel heart surgery registry shows excellent results for TAVR Four years after its approval in the United States, transcatheter aortic valve replacement (TAVR) continues to evolve and demonstrate positive outcomes for patients with aortic stenosis, a common heart problem.
Biophysicists develop a model for arterial thrombus formation Biophysicists have developed a mathematical model of arterial thrombus formation, which is the main cause of heart attacks and strokes. The scientists described the process of platelet aggregation as being similar to the popular video game Tetris and derived equations that allowed them to reproduce the wave process of platelet aggregate formation in a blood vessel.
Genes linked to stress-triggered heart disease identified For the first time, genetic risk factors have been identified that are linked to stress-induced cardiomyopathy (SIC), a rare type of heart disease. Patients with SIC generally show no symptoms until they suffer some form of intense emotional or physiological distress. For this reason the disorder is sometimes referred to as 'broken heart syndrome.'
Genetic link between heart and neurodevelopmental disease Children with significant congenital heart disease have a far better chance of surviving today than in decades past, thanks to major advances in surgery. But some infants who recover from repairs to their hearts later show the effects of delays in brain development. Researchers reported exome sequence analyses of more than 1,200 children and their parents and showed that children with both congenital heart disease and neurodevelopmental delays share certain genetic mutations that thwart the normal development of both the heart and the brain

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