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Wednesday, June 10, 2015

Cardiovascular Research:Researchers identify new genetic cause of arrhythmia ♦ Restless legs syndrome to increased risk of stroke ♦ New genetic mutation in aortic disease allows better diagnosis

Researchers identify new genetic cause of arrhythmia and develop therapy A rare and deadly form of inherited arrhythmia has been identified by researchers, who have developed a method to treat it. Arrhythmia is a malfunction of the heart's electrical system that causes irregular heartbeats.  
Study links severe restless legs syndrome to increased risk of stroke Increased restless legs syndrome severity is associated with subsequent increased risk of stroke, researchers report. The study group comprised 72,916 female registered nurses ages 41-58 years in 2005, free of diabetes, stroke, and pregnancy at the baseline.
Discovery of new genetic mutation in aortic disease allows better diagnosis and brings personalised medicine a step closer Thoracic aortic aneurysm and dissection (TAAD), an enlargement or tearing of the walls of the aorta in the chest, is, together with abdominal aortic aneurysms, responsible for about 2% of all deaths in Western countries. The aorta is the largest artery in the body, and carries blood from the heart. About one out of every five patients with TAAD has a family member with the same disorder, therefore indicating a genetic cause.  However, the relevant genetic mutations discovered so far only explain about 30% of all cases
. Images reveal structure of heart cells that may hold heart attack clues Newly released images revealing the 'bicycle spoke' structure of a heart cell may hold key clues to reducing damage from a heart attack. Using a novel type of electron microscopy, researchers produced 3D images of a healthy heart cell at nanoscopic scale which shows part of their structure is arranged like spokes on a wheel.

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