Genome mining effort discovers 19 new natural products in four years It took a small group of researchers only four years -- a blink of an eye in pharmaceutical terms -- to scour a collection of 10,000 bacterial strains and isolate the genes responsible for making 19 unique, previously unknown phosphonate natural products, researchers report. Each of these products is a potential new drug. One of them has already been identified as an antibiotic
New method to treat antibiotic resistant MRSA: Bacteriophages A senior molecular biology major knows MRSA as the infection that took his dad's leg. Now he is exacting revenge on the bacteria by unlocking the power of a new MRSA-killer: bacteriophage.
Combo of three antibiotics can kill deadly staph infections Three antibiotics that, individually, are not effective against a drug-resistant staph infection can kill the deadly pathogen when combined as a trio, according to researchers. They have killed the bug -- methicillin-resistant Staphylococcus aureus -- in test tubes and laboratory mice, and believe the same strategy may work in people.
Strategies to decrease bacterial colonization Among the bacterial infections that are most difficult to treat, chronic infections associated with bacterial biofilms are one of the most hazardous. Bacterial biofilms are densely packed communities of microbial cells surrounded with secreted polymers. A chemist's new doctoral thesis has studied ways to decrease the bacterial colonization.
Researchers work to improve antibiotic effectiveness A new group of antibiotics has been discovered that may provide relief to some of the more than two million people in the United States affected by antibiotic resistance.