Stressed-out parasites: Overcoming drug-resistant malaria Drug resistance to the critical antimalarial therapeutics of the artemisinin family has emerged in Southeast Asia, highlighting the need to understand how these drugs work and how they can be used more effectively. Artemisinins may function by chemically damaging the malaria parasite's proteins, causing them to activate a cellular stress response
Discovery could impact study of chronic pain conditions Researchers have uncovered the critical role in pain processing of a gene associated with a rare disease. Their breakthrough paves the way for a better understanding of chronic pain
Missing genetic link found in a challenging immune disease In the largest genome-wide analysis to date of common variable immunodeficiency disorder, scientists have identified a gene that may be a 'missing link' between overactive and underactive immune activity.
Finding effective, cost-effective treatments for complex wounds Two new papers identify which of the hundreds of available treatments for complex wounds are most likely to be effective and which are most likely to be cost-effective. Complex wounds are a significant burden on patients and on the economy, costing the North American health-care system $10 billion a year.
New Ebola treatment effective three days after infection A post-exposure treatment that is effective against a specific strain of the Ebola virus that killed thousands of people in West Africa has been developed. The treatment uses a sequence specific short strand of RNA, known as siRNA, designed to target and interfere with the Ebola virus, rendering it harmless.
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