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Monday, April 13, 2015

Cancer Research: Cancer-suppressing proteins ♦ Two cancer research fronts to join forces ♦ Cancers drug resistant mechanism revealed

Telomeres and cancer mortality: The long and the short of it Telomeres are short stretches of repeated nucleotides that protect the ends of chromosomes. In somatic cells, these protective sequences become shorter with each cellular replication until a critical length is reached, which can trigger cell death. At the conclusion of their study, the authors conclude, "We speculate that long telomeres may represent a survival advantage for cancer cells, allowing multiple cell divisions leading to high cancer mortality."
Breakthrough in cancer research: Cancer-suppressing proteins Two cancer-suppressing proteins that could hold a key to controlling cancer cell growth and development have been discovered by researchers. The previously undiscovered proteins were found during ongoing research on the ubiquitin system.
Call to action for two cancer research fronts to join forces Targeting the genetic drivers of cancer works in clinical trials, but cancers often resurface shortly thereafter. Immunotherapy -- which primes a patient's immune cells to attack tumors -- offers a longer-lasting response, but only in a fraction of people. The way forward, argue experts, is to shift funding and research priorities so that these complementary approaches can be combined
Drug resistant mechanism revealed for a new targeted cancer therapy New research shines a light on identifying ‘hot spots’ in drug-resistant mutations involving a certain protein found to influence cancer growth.

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