Cancer genes turned off in deadly brain cancer Scientists have identified a small RNA molecule that can suppress cancer-causing genes in mice with glioblastoma multiforme, a deadly and incurable type of brain tumor. While standard chemotherapy drugs damage DNA to stop cancer cells from reproducing, the new method stops the source that creates those cancer cells. The approach could also potentially be used for gene silencing in other cancers and diseases of genetic origin.
Researchers combine common genetic variants, other factors to improve breast cancer risk prediction Recent large-scale genomic analyses have uncovered dozens of common genetic variants that are associated with breast cancer. Each variant, however, contributes only a tiny amount to a person’s overall risk of developing the disease. Now an international team of researchers has combined 77 of these common genetic variants into a single risk factor that can be used to improve the identification of women with an elevated risk of breast cancer. This factor, known as a polygenic risk score, was built from the genetic data of more than 67,000 women.
Potential chemoresistance after consuming fatty acid in fish Researchers found that consuming the fish herring and mackerel, as well as three kinds of fish oils, raised blood levels of the fatty acid 16:4(n-3), which experiments in mice suggest may induce resistance to chemotherapy used to treat cancer
One dollar blood test using gold nanoparticles outperforms PSA screen for prostate cancer A test that uses gold nanoparticles to detect early-stage prostate cancer costs less than $1, returns results in minutes and is more accurate than standard PSA screening, pilot studies show. The new technique leverages the ability of gold nanoparticles to attract cancer biomarkers