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Tuesday, April 7, 2015

Cancer Research; Safety of magic anti-cancer bullet ♦ Cancers highjack powerhouses of cells ♦ Sound separates cancer cells from blood samples

Sound separates cancer cells from blood samples Separating circulating cancer cells from blood cells for diagnostic, prognostic and treatment purposes may become much easier using an acoustic separation method and an inexpensive, disposable chip.
Mechanism that drives melanoma to metastasize identified  In a unique partnership demonstrating excellence in "team science," investigators identified a role for the molecule CXCR3 (widely known to regulate the migration of immune cells) as a key mediator of melanoma metastasis. The significance of this work is its descriptions of alternative mechanisms by which tumors move and settle in new locations.
New target for anticancer drugs: RNA  Messenger RNAs -- the working copies of genes that are used to assemble proteins -- have typically been ignored as drug targets because they all look about the same. But researchers have found that a subset of mRNAs -- many of which have been linked to cancer -- have unique tags. These short RNA tags bind to a protein, eIF3, that regulates translation at the ribosome, making the binding site a promising target for anticancer drugs.
Researchers put safety of magic anti-cancer bullet to test The first systematic study has been carried out analyzing the safety of so-called upconversion nanoparticles that may be used to treat skin cancer and other skin diseases. This study is one of the most important steps on the path to new, safe and effective methods to diagnose and treat cancer.

Common cancers highjack powerhouses of cells  In a breakthrough in the understanding of how cancer does its deadly work, researchers have shown that many cancers -- including nearly all pancreatic cancers -- enslave and deform mitochondria, the powerhouses of cells, to create an environment more conducive to tumor growth

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