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Thursday, July 30, 2015

Brain Research:Where memory is encoded and retrieved ♦ Key enzyme implicated in Alzheimer's ♦ Brain chemicals that keep wakefulness in check

Naturally occurring protein fragment found in the brain inhibits key enzyme implicated in Alzheimer's disease A natural protein fragment produced in the brain can act as an inhibitor of a key enzyme implicated in the onset of Alzheimer's disease, researchers have discovered for the first time. This is a finding that could lead to the development of new drugs to treat the disease, they say.
Where memory is encoded and retrieved: New findings in a long-standing debate Are the same regions and even the same cells of the brain area called hippocampus involved in encoding and retrieving memories or are different areas of this structure engaged? This question has kept neuroscientists busy for a long time. Researchers have now found out that the same brain cells exhibit activity in both processes.
Key factor for stability of capillaries in brain identified The brain needs a lot of oxygen – so every last corner of the brain’s tissue is served by a dense network of fine blood vessels. When these capillaries are damaged by high blood pressure or age, doctors call the condition cerebral small vessel disease. They estimate this is the cause of around one in five strokes, and that the condition may also lead to certain forms of dementia.
Study finds brain chemicals that keep wakefulness in check Mice that have a particular brain chemical switched off become hyperactive and sleep for just 65 per cent of their normal time, a new study shows. This discovery could help researchers to develop new drugs that promote better sleep, or control hyperactivity in people with the medical condition mania

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