Iron-containing inflammatory cells seen in Alzheimer's brains Examining post-mortem tissue from the brains of people with Alzheimer's disease, investigators identified what appear to be iron-containing microglia in a particular part of the hippocampus, a key brain structure whose integrity is critical to memory formation.
Novel monoclonal antibodies show promise for Alzheimer's disease treatment Scientists have evidence that monoclonal antibodies they developed may provide the blueprint for effective treatments for Alzheimer's disease and other neurodegenerative diseases, such as Parkinson's disease.
New treatment avenue to prevent serious retinal detachment Wet age-related macular degeneration (AMD) is the leading cause of severe vision loss in older individuals. AMD and other serious chronic eye problems that affect younger individuals result when fluid accumulates abnormally under or within the retina. A new study shows for the first time that the release of substances from mast cells may be a causal factor in this type of eye pathology, and inhibitors of this release may offer new ways to treat serous retinal detachment.
Specific protein as missing link for earliest known change in Alzheimer's pathology A recent study implicates a new culprit in Alzheimer's disease development. A precursor of an amyloid beta peptide acts at the earliest stage of Alzheimer's to initiate a range of abnormalities leading to the loss of groups of neurons critical for memory formation.
Poor diabetes control found in older Americans Only one in three older Americans has their diabetes under control as measured by guidelines set by the American Diabetes Association, new research suggests. Some argue that ADA guidelines may be too stringent for some older adults. But even using less stringent measures, the researchers found, there are still many older Americans whose diabetes is not well managed, a condition that can lead to multiple long-term health problems ranging from kidney disease to blindness.