Some adverse drug events not reported by manufacturers to FDA by 15-day mark About 10 percent of serious and unexpected adverse events are not reported by drug manufacturers to the US Food and Drug Administration under the 15-day timeframe set out in federal regulations.
In CRISPR advance, scientists successfully edit human T cells Scientists have devised a new strategy to precisely modify human T cells using the genome-editing system known as CRISPR/Cas9. Because these immune-system cells play important roles in a wide range of diseases, from diabetes to AIDS to cancer, the achievement provides a versatile new tool for research on T cell function, as well as a path toward CRISPR/Cas9-based therapies for many serious health problems.
Researchers identify model to predict successful wound healing Battlefield surgeons and civilian physicians could have a powerful new tool to help patients recover from traumatic injuries, including life-threatening wounds from explosions. Researchers have identified a model to predict the chances for successful wound healing in individual patients.
Some vaccines support evolution of more-virulent viruses Scientific experiments with the herpesvirus such as the one that causes Marek's disease in poultry have confirmed, for the first time, the highly controversial theory that some vaccines could allow more-virulent versions of a virus to survive, putting unvaccinated individuals at greater risk of severe illness. The research has important implications for food-chain security and food-chain economics, as well as for other diseases that affect humans and agricultural animals.
Strong link between delirium, inflammation in older patients Delirium is an acute state of confusion that often affects older adults following surgery or serious illness. Now a study confirms that inflammation -- an immune response that develops when the body attempts to protect itself from harmful stimuli -- plays a role in the onset of delirium.
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