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Thursday, May 28, 2015

Cancer Research: Nanotechnology identifies brain tumor types ♦ Tumor surroundings are shown to affect progression ♦ Resistant breast cancer mechanism revealed

Nanotechnology identifies brain tumor types through MRI 'virtual biopsy' A tiny drug-delivery system has been invented that can identify cancer cell types in the brain through 'virtual biopsies' and then attack the molecular structure of the disease. The results could be used to deliver nano-scale drugs that can distinguish and fight tumor cells in the brain without resorting to surgery.
How DNA is organized in our cells A critical role for two proteins in chromatin structure has been uncovered by researchers. Their breakthrough helps explain how DNA is organized in our cells. This discovery could lead to a better understanding of what causes certain types of cancer, such as lymphoma.
Therapy-resistant breast cancer mechanism revealed A cluster of defined, non-coding RNAs are mechanistically involved in endocrine therapy resistance in human breast cancer cells. Furthermore, resveratrol, a kind of polyphenol, was found to repress these RNAs and inhibit the proliferative activity of breast cancer cells which had acquired resistance
Two new, very large classes of RNAs found to be linked to cancer biomark Two new classes of RNAs have been identified that are closely associated with a protein known to be a prognostic biomarker for breast cancer and could play a role in progression of prostate cancer.
Tumor surroundings are shown to affect progression of different cancer subtypes Our environment can have a major impact on how we develop, and it turns out it's no different for cancer cells. A team of researchers reports that two different mouse models of breast cancer progressed differently based on characteristics of the tumor microenvironment -- the area of tissue in which the tumor is embedded.

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