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Wednesday, July 15, 2015

Health Research: Stem cells provide lasting pain relief in mice ♦ New compounds may treat depression rapidly with few side effects ♦ Skin cancer marker plays critical role in tumor growth

Patients over 50 with ulcerative colitis (UC), a chronic disease of the colon, who undergo surgery to treat their condition live longer than those who are treated with medications.
Researchers have identified a promising stem cell based-therapy to address the chronic pain that affects more than one-third of the US adult population. In mice, bone marrow stromal cells were found to provide lasting relief for chronic pain caused by nerve damage. The findings also may advance cell-based therapies in chronic pain conditions, lower back pain and spinal cord injuries.
A new study has identified promising compounds that could successfully treat depression in less than 24 hours with few side effects. The compounds could offer significant advantages over current antidepressant medications.
The protein keratin 17 -- the presence of which is used in the lab to detect and stage various types of cancers -- is not just a biomarker for the disease, but may play a critical role in tumor growth, scientists suggest.
Renal cell carcinomas are one of the most common types of cancer. In order to preserve its wide range of functions, every effort is made not to remove the entire kidney, but rather just a portion of it. A surgical method that preserves long-term renal function has now been carried out successfully.


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