Tuesday, July 7, 2015

Senior Health: Alzheimer's disease works differently in patients with Down Syndrome ♦ Omega-3 supplements help with preclinical Alzheimer's disease ♦ Age-related cognitive decline tied to immune-system molecule

SSRI antidepressants taken for menopausal symptoms may boost bone fracture risk The class of antidepressants known as SSRIs (selective serotonin reuptake inhibitors), taken to curb menopausal symptoms, may boost bone fracture risk.
Alzheimer's disease works differently in patients with and without Down Syndrome A study revealed differences in the way brain inflammation -- considered a key component of AD-- is expressed in different subsets of patients, in particular people with Down syndrome (DS) and AD.
Omega-3 supplements, antioxidants may help with preclinical Alzheimer's disease Here's more evidence that fish oil supplementation and antioxidants might be beneficial for at least some people facing Alzheimer's disease: A new report describes the findings of a very small study in which people with mild clinical impairment, such as those in the very early stages of the disease, saw clearance of the hallmark amyloid-beta protein and reduced inflammation in neurological tissues.
Older patients with traumatic spinal cord injuries less likely to get surgery Older patients with traumatic spinal cord injuries are less likely to receive surgery compared with younger patients and they experience a significant lag between injury and surgery.
Age-related cognitive decline tied to immune-system molecule A blood-borne molecule that increases in abundance as we age blocks regeneration of brain cells and promotes cognitive decline. The molecule in question, known as beta-2 microglobulin, or B2M, is a component of a larger molecule called MHC I, which plays a major role in the adaptive immune system. A growing body of research indicates that the B2M-MHC I complex, which is present in all cells in the body except red blood cells and plasma cells, can act in the brain in ways not obviously related to immunity--guiding brain development, shaping nerve cell communication, and even affecting behavior

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