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Friday, May 1, 2015

Cancer Research: Aspirin fights colorectal cancer and cervical cancer ♦ Researchers solve a lingering mystery of cancer cell biology ♦ Bowel cancer patient exercise to achieve health benefits

Two-thirds of bowel cancer patients aren't advised to exercise despite health benefits More than two-thirds of bowel cancer patients say they weren't advised to exercise regularly after their diagnosis – despite evidence that brisk physical activity is linked to better survival in bowel cancer.
Frequent aspirin use reduces risk of cervical cancer by nearly half Long-term and frequent use of aspirin is associated with significantly decreased risk of cervical cancer, according to a study.12,900 new cases of cervical cancer will be diagnosed and 4,100 women will die from the disease in 2015.
Settling an old debate: Researchers solve a lingering mystery of cancer cell biology German biologist Theodor Boveri observed early in the last century that cancer cells often harbor multiple copies of a subcellular structure that he had previously named the centrosome. He was also the first to suggest that the extra centrosomes drive cancer. Biologists have since learned a great deal about the structure and many functions of Boveri’s “special organ of cell division.” But why cancer cells harbor multiple copies of this organelle has remained unanswered. So has the question of whether healthy human cells even require centrosomes to divide. Now, 101 years after Boveri aired his suspicions, a paper may have some answers.

How aspirin fights colorectal cancer Taking aspirin reduces a person's risk of colorectal cancer, but the molecular mechanisms involved have remained unknown until a recent discovery. found that aspirin might exert its chemopreventive activity against colorectal cancer, at least partially, by normalizing the expression of epidermal growth factor receptor (EGFR) in gastrointestinal precancerous lesions. EGFR is overexpressed in about 80 percent of cases involving colorectal cancer, the third-leading cause of cancer-related death in the United States.

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