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Wednesday, May 6, 2015

Cancer Research: Telomere changes predict cancer ♦ Surgery for terminal cancer patients still common ♦ statin use may lower risk of lung cancer death

Prolonged statin use may lower risk of lung cancer death Lung cancer patients who used statins in the year prior to a lung cancer diagnosis or after a lung cancer diagnosis had a reduction in the risk of death from the disease.
Surgery for terminal cancer patients still common The number of surgeries performed on terminally ill cancer patients has not dropped in recent years, despite more attention to the importance of less invasive care for these patients to relieve symptoms and improve quality of life
Telomere changes predict cancer A distinct pattern in the changing length of blood telomeres, the protective end caps on our DNA strands, can predict cancer many years before actual diagnosis. The pattern, which spanned 13 years before cancer diagnosis, could yield a new biomarker to predict cancer development with a blood test. This is the first reported trajectory of telomere changes over the years in people developing cancer.
Racial differences in male breast cancer outcomes While black and white men under age 65 diagnosed with early-stage breast cancer received similar treatment, blacks had a 76 percent higher risk of death than whites. Male breast cancer is a rare disease, accounting for less than 1% of all cancers in men and approximately 2% of all breast cancers in the United States. Black men have a higher incidence of breast cancer and are more likely to be diagnosed with breast cancer at a younger age.
Scientists dramatically improve method for finding common genetic alterations in tumors Scientists have developed a significantly better computer tool for finding genetic alterations that play an important role in many cancers but were difficult to identify with whole-genome sequencing. The tool is an algorithm called CONSERTING.

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