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Tuesday, July 7, 2015

Cardiovascular Research:Two bio markers linked to severe heart disease ♦ Heart attack treatment hypothesis 'busted ♦ Fundamental beliefs about atherosclerosis overturned

Two bio markers linked to severe heart disease found A first-of-its-kind animal model to pinpoint two biomarkers that are elevated in the most severe form of coronary disease has been developed by scientists.
Heart attack treatment hypothesis 'busted' Researchers have long had reason to hope that blocking the flow of calcium into the mitochondria of heart and brain cells could be one way to prevent damage caused by heart attacks and strokes. But in a study of mice engineered to lack a key calcium channel in their heart cells, scientists appear to have cast a shadow of doubt on that theory.
New blood pressure guidelines may lead to under treatment of older adults In 2014, the Joint National Committee released the eighth update to the blood pressure guidelines (JNC8P). These guidelines included a controversial decision to change the blood pressure goal that may lead to under treatment of adults 60 years of age or older. The JNC8P guidelines set a less stringent goal blood pressure of < 150/90 mmHg for individuals 60 years of age or older compared to the previous <140/90 mmHg goal.
Reducing stroke damage may be next for optical coherence tomography technology widely used in vision healthcare A new article reports on use of optical coherence tomography to obtain high-resolution images showing blood-flow dynamics in the brain before, during, and after stroke-like states. The information may ultimately enable clinicians to reduce stroke damage.
Fundamental beliefs about atherosclerosis overturned Doctors' efforts to battle the dangerous atherosclerotic plaques that build up in our arteries and cause heart attacks and strokes are built on several false beliefs about the fundamental composition and formation of the plaques. These new discoveries will force researchers to reassess their approaches to developing treatments and discard some of their basic assumptions about atherosclerosis.

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